I adore this moisturizer and alternate use along with the Triple Strength Advanced Wrinkle Smoother. I love them both. For me, the ingredients are different and I believe each has significant benefit. So rather than just use one, I use both and alternate use. That works really well for me. I apply after HydroShield Serum or Firmatone which I also rotate use. Staples in my skin care regimen. I also like the Rx Transforming Peel which I use every 10-14 days.