I use this product in the AM to help combat the wrinkles around my eye area. I won't say they've disappeared completely, but they have dimished due to the assistance of this product. I can't expect to erase 50+ years of smile lines in a few short weeks, but Dr. Denese's products have performed miracles on my skin! One can only hope that our skin will look as flawless as hers with continued use of her perfect line of products. Well worth the money for a product that delivers results.